Shouldn't be anything different for 64-bit Windows, that's what many of us are using I suspect

The ultimate simplification for all this will be the Adapt Authoring Tool (currently being feverishly worked on) which, whilst I'm sure will require a small amount of technical know-how - and probably a bit of reading too, sorry - to get running, should thereafter not require technical knowledge if you want to build and publish content.

We've been gathering some of the common issues here: https://github.com/adaptlearning/adapt_framework/wiki/Common-Issues - if you have time to contribute anything to this list that'd be most welcome as it's often difficult to get enough info about the issues people encounter to make them worth documenting.